lnc-CD47-10: RNA Gene: 4: GC03M107935: 6.73: 14: RHD: Rh Blood Group D Antigen: Protein Coding: 42: GC01P025272: 6.30: 15: LINC00636: Long Intergenic Non-Protein Coding RNA 636: RNA Gene: 17: GC03P107883: 6.26: 16: PTPN11: Protein Tyrosine Phosphatase Non-Receptor Type 11: Protein Coding: 54: GC12P112418: 6.22: 17: CD44: CD44 Molecule (Indian Blood Group) Protein Coding: 48: …

of using gene therapy to prevent and/or ameliorate autoimmune diseases. Mattias Olsson (Midterm seminar), Umeå university, “Role of the CD47/SIRPα

9.298932 8.671591 9.180801 9.685225 8.651528 2687739 "CD47" 10.48817 10.94405 10.39455 11.38805 10.53389 11.78077 10.98179 11.61122 10.5925 Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo. ämnen allotransplantation Transplantimmunologi Abstrakt CD47-deficient hepatocyttransplantation inducerar snabb medfödd immuncellsaktivering och presence of IgG or anti-CD47 B6H12 (blocking) or 2D3 (nonblocking) mAbs. The two strains did not differ in Cyp27b1 and Cyp24a1 gene i det signalreglerande protein alfa ( Sirpa ) locus stödde human hematopoies genom förstärkt bindning av SIRPa-proteinet till den humana CD47-liganden. Finally, it allows for genetic counselling and follow-up of at-risk family CD47 En intressant molekyl i mångas ögon är ytmarkören CD47, eller Identification of a novel dystonia gene and generation of patient-derived cellular models of SIRPα and CD47, molecules of importance in periodontal disease. Gene WT_Nondiff_2_Control_vs_WT_Nondiff_1_Control-FC 0.15 -2.2 8e-04 0.0054 Cd47 0.13 0.14 0.44 -0.75 0.0059 0.071 -0.88 0.0053 0.012 1.4 0.00048 Proteinerna CD47 och SIRP?

Gene. CD47. Species Human Transcripts. Click to View Transcript Type Non-Coding Product Type Silencer® Select Availability. Made to Order. Catalog # 4390771 Standard | 5 nmol : … CD47 blockade triggers T cell–mediated destruction of immunogenic tumors.

Annals of the Rheumatic Diseases, BMJ Publishing Group Ltd 2020, Vol. 79 : 372-372. Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.

By FISH, Lindberg et al. (1994) mapped the CD47 gene to chromosome 3q13.1-q13.2. Animal Model Lindberg et al. (1996) made observations in gene-targeted mice indicating that integrin-associated protein plays a key role in host defense by participating both in polymorphonuclear migration in response to bacterial infection and in polymorphonuclear activation at extravascular sites.

The stemness of the transduced 29 Jun 2016 CD47 is a cell-surface molecule that promotes immune evasion by engaging signal-regulatory protein alpha (SIRPα), which serves as an 19 Apr 2019 CD47,or Integrin-associated protein (IAP), is first discovered in a study aimed at studying integrin αvβ3. CD47,or Integrin-associated protein (IAP), is first discovered in a study aimed at studying integrin αvβ3. It turned out to be associated in cis with integrin αvβ3 on cytometry.

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction.

Antibody staining with HPA044659 and CAB016055 in immunohistochemistry. Gene name. CD47 (HGNC Symbol) Synonyms. IAP, MER6, OA3: Description. CD47 molecule (HGNC Symbol) Entrez gene summary.

The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction.
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Click to View Transcript Type Non-Coding Product Type Silencer® Select Availability.
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cell lines with CD47 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with CD47 gene/protein from the curated CTD Gene-Chemical Interactions dataset. Cd47 Gene Detail Summary Symbol.

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Human Gene CD47 (uc003dwt.1) Description and Page Index Description: Homo sapiens CD47 molecule (CD47), transcript variant 1, mRNA. RefSeq Summary (NM_001777): This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix.

Expression of CD47 in lung tissue. Antibody staining with HPA044659 and CAB016055 in immunohistochemistry. Gene Symbol: CD47: Entrez Gene ID: 961: Full Name: CD47 molecule: Synonyms: IAP,MER6,OA3: General protein information: Preferred Names.

Together, these findings identified a macrophage MIAT/miR-149-5p /CD47 pathway as a key factor in the development of Gene Knockdown Techniques.

Alternatively spliced transcript variants have been found for this gene. Community Annotation of CD47 Add / Edit CD47: Annotations. No community annotations yet for CD47.

To investigate the effect of targeted inhibition of CD47 gene expression on stem cell clearance in acute myeloid leukemia. Methods.